Ashley Russell, Ph.D.

Ashley Russell, Ph.D.
Assistant Professor of Biochemistry and Molecular Biology, Biology
Office Phone
Office Location
174 Benson

Mailing Address:
ERIE PA 16563

    Dr. Russell is an Erie native and Behrend graduate. She received her PhD in Neuroscience from West Virginia University and completed her post-doctoral fellowship at Johns Hopkins.

    Research Interests

    Extracellular vesicles, neuroinflammation, non-coding RNAs, stress, development, biomarker discovery


    Size exclusion chromatography for separating extracellular vesicles from conditioned cell culture media, Journal of Visualized Experiments - May 13, 2022
    Collaborators: Madison Jones; Samantha Manioci

    The Future of Work in Erie County, Jefferson Educational Society - February, 2022
    Collaborators: Jacob Bartko; Susannah Faulkner; Matt Flowers; Thomas Glasoe; Melinda Hall; Paul Hirsch; Browdy Howard; Victor Hudson; Michelle Jaggi; Alyssa Johnson; Stephanie King; Tammie Lentz; Jake Marsh; Samuel McGarvey; Justin Norris; Chelsea Oliver; Sara Provencio; Jennifer Snopko; Megan Stevenson; Corrine Thomas; Adam Welsh; Larry Wheaton; Karin Wickwire; Brian Wilking; Ben Wilson

    Cigarette smoke-induced extracellular vesicles of dendritic cells alter T-cell activation and HIV replication, Toxicology Letter - February 16, 2022
    Collaborators: Zhaohao Liao, Secondary Author; Mercedes Tkach, Co-Author; Patrick Tarwater, Co-Author; Matias Ostrowski, Co-Author; Clotilde Théry, Co-Author; Kenneth Witwer, Co-Author

    miR-146a dysregulates energy metabolism during neuroinflammation, Journal of Neuroimmune Pharmacology - May 24, 2021
    Collaborators: Sujung Jun; Wei Wang; Darren Gemoets; Saumyendra Sarkar; James Simpkins; Candice Brown

    Intermittent lipopolysaccharide exposure significantly increases cortical infarct size and impairs autophagy, ASN Neuro - February 24, 2021
    Collaborators: John Cavendish; Ali Rai; Maya Vannoy; Ahmad Dakhlallah; Heng Hu; Xeufang Ren; Amal Amer; Candice Brown; Clay Marsh; James Simpkins; Duaa Dakhlallah

    Hitting the bullseye: Are extracellular vesicles on target?, Journal of Extracellular Vesicles - November 29, 2020
    Collaborators: Nicole Noren Hooten; María Yáñez-Mó; Array DeRita; Peter Quesenberry; Bharat Ramratnam; Paul Robbins; Dolores Di Vizio; Sicheng Wen; Kenneth Witwer; Lucia Languino

    Biological membranes in EV biogenesis, stability, uptake, and cargo transfer: an ISEV position paper arising from the ISEV membranes and EVs workshop, Journal of Extracellular Vesicles - 2019
    Collaborators: Alexandra Sneider; Kenneth Witwer

    Extracellular vesicles secreted in response to cytokine exposure increase mitochondrial oxygen consumption in recipient cells, Frontiers in Cellular Neuroscience - 2019
    Collaborators: Sujung Jun; Saumyendra Sarkar; Werner Geldenhuys; Sara Lewis; Stephanie Rellick; James Simpkins

    Over-expression of miR-34a induces rapid cognitive impairment and Alzheimer’s disease-like pathology, Brain Research - 2019
    Collaborators: Saumyendra Sarkar; Elizabeth Engler-Chiurazzi; John Cavendish; Jessica Povroznik; Dominic Quintana; Peter Mathers; James Simpkins

    Hypoxia-reoxygenation of primary astrocytes results in a redistribution of mitochondrial size and mitophagy, Mitochondrion - 2018
    Collaborators: Dominic Quintana; Jorge Garcia; Saumyendra Sarkar; Sujung Jun; Elizabeth Engler-Chiurazzi; John Cavendish; James Simpkins

    MicroRNAs and the genetic nexus of brain aging, neuroinflammation, neurodegeneration, and brain trauma, Aging and Disease - 2018
    Collaborators: Saumyendra Sarkar; Elizabeth Engler-Chiurazzi; Keyana Porter; James Simpkins

    Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines, Journal of Extracellular Vesicles - 2018
    Collaborators: Clotilde Thery; Kenneth Witwer

    miR-34a and stroke: Assessment of non-modifiable biological risk factors in cerebral ischemia, Neurochemistry International - 2018
    Collaborators: Xeufang Ren; Elizabeth Engler-Chiurazzi; Saumyendra Sarkar; Stephanie Rellick; Sara Lewis; Deborah Corbin; Jared Clapper; James Simpkins

    TNF-α and beyond: Rapid mitochondrial dysfunction mediates TNF-α-induced neurotoxicity - 2016
    Collaborators: Danielle Doll; Saumyendra Sarkar; James Simpkins

    Lipopolysaccharide exacerbates infarct size and results in worsened post-stroke behavioral outcomes, Behav Brain Funct - 2015
    Collaborators: Danielle Doll; Elizabeth Engler-Chiurazzi; Sara Lewis; Heng Hu; Xeufang Ren; James Simpkins


    Ph D, Neuroscience, West Virginia University

    BS, Psychology, Penn State Behrend